Is the plan of God thwarted by the evil actions of men? Some people including atheists would say yes – there is no place for evil in a world that God created. However, biblically and experientially we see God bringing good out of evil more often than we realize.
Remember Joseph talking to his brothers says “what you meant for evil, God meant for good. Think of how comforting this must be to someone who commits a serious sin and wants to repent. The severity of the sin they commit may be the very thing that causes them to ask for forgiveness and bring them to salvation!
J Warner Wallace does a great job of explaining how God can and does use evil to fulfill His plan:
http://coldcasechristianity.com/2016/would-god-actually-use-evil-to-draw-us-to-himself/